Cardene SR Full Prescribing Information



	Full Prescribing Information To view the full Prescribing Information for CARDENE SR please click on the link below. CARDENE SR Prescribing Information To view PDF documents, you must have the Adobe® Acrobat® Reader® installed on your computer.

Important Safety Information
CARDENE SR is contraindicated in patients with known hypersensitivity to the drug and in patients with advanced aortic stenosis. Reduction of diastolic pressure by any means in these patients may worsen rather than improve myocardial oxygen balance. Caution is advised when administering Cardene SR to patients with angina, congestive heart failure (particularly those who are also taking a ß-blocker), impaired renal or hepatic function, or severe left ventricular dysfunction. Cardene SR provides no protection against the dangers of abrupt ß-blocker withdrawal. The immediate release form of nicardipine caused an increase in angina in 7% of patients compared to 4% on placebo. The most common adverse events were headache (6.2%), pedal edema (5.9%), vasodilation (4.7%), increased angina (4%), palpitation (2.8%), nausea (1.9%), and dizziness (1.6%). Cyclosporine levels should be monitored closely during therapy.

Makers of

and